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Depleting SOX2 improves ischemic stroke via lncRNA PVT1/microRNA-24-3p/STAT3 axis

OBJECTIVES: Studies have widely explored in the filed of ischemic stroke (IS) with their focus on transcription factors. However, few studies have pivoted on sex determining region Y-box 2 (SOX2) in IS. Thus, this study is launched to figure out the mechanisms of SOX2 in IS. METHODS: Rat middle cere...

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Detalles Bibliográficos
Autores principales: Chen, Zhongjun, Fan, Tieping, Zhao, Xusheng, Zhang, Zhichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439026/
https://www.ncbi.nlm.nih.gov/pubmed/34521353
http://dx.doi.org/10.1186/s10020-021-00346-8