Ceftriaxone therapy attenuates brain trauma in rats by affecting glutamate transporters and neuroinflammation and not by its antibacterial effects

BACKGROUND: Ceftriaxone is a β-lactam antibiotic used to treat central nervous system infections. Whether the neuroprotective effects of ceftriaxone after TBI are mediated by attenuating neuroinflammation but not its antibacterial actions is not well established. METHODS: Anesthetized male Sprague–D...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Sher-Wei, Su, Hui-Chen, Nyam, Tee-Tau Eric, Chio, Chung-Ching, Kuo, Jinn-Rung, Wang, Che-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439027/
https://www.ncbi.nlm.nih.gov/pubmed/34521349
http://dx.doi.org/10.1186/s12868-021-00659-8