MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer

BACKGROUND: Cancer cells develop resistance to chemotherapeutic intervention by excessive formation of stress granules (SGs), which are modulated by an oncogenic protein G3BP2. Selective control of G3BP2/SG signaling is a potential means to treat non-small cell lung cancer (NSCLC). METHODS: Co-immun...

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Detalles Bibliográficos
Autores principales: Li, Haichang, Lin, Pei-Hui, Gupta, Pranav, Li, Xiangguang, Zhao, Serena Li, Zhou, Xinyu, Li, Zhongguang, Wei, Shengcai, Xu, Li, Han, Renzhi, Lu, Jing, Tan, Tao, Yang, Dong-Hua, Chen, Zhe-Sheng, Pawlik, Timothy M., Merritt, Robert E., Ma, Jianjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439062/
https://www.ncbi.nlm.nih.gov/pubmed/34521423
http://dx.doi.org/10.1186/s12943-021-01418-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439062/
https://www.ncbi.nlm.nih.gov/pubmed/34521423
http://dx.doi.org/10.1186/s12943-021-01418-3

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