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Chronic inflammation-induced senescence impairs immunomodulatory properties of synovial fluid mesenchymal stem cells in rheumatoid arthritis

BACKGROUND: Although the immunomodulatory properties of mesenchymal stem cells (MSCs) have been highlighted as a new therapy for autoimmune diseases, including rheumatoid arthritis (RA), the disease-specific characteristics of MSCs derived from elderly RA patients are not well understood. METHODS: W...

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Detalles Bibliográficos
Autores principales: Lee, Hyeon-Jeong, Lee, Won-Jae, Hwang, Sun-Chul, Choe, Yongho, Kim, Saetbyul, Bok, Eunyeong, Lee, Sangyeob, Kim, Seung-Joon, Kim, Hyun-Ok, Ock, Sun-A, Noh, Hae-Sook, Rho, Gyu-Jin, Lee, Sang-Il, Lee, Sung-Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439066/
https://www.ncbi.nlm.nih.gov/pubmed/34521481
http://dx.doi.org/10.1186/s13287-021-02453-z