Cargando…

Chronic inflammation-induced senescence impairs immunomodulatory properties of synovial fluid mesenchymal stem cells in rheumatoid arthritis

BACKGROUND: Although the immunomodulatory properties of mesenchymal stem cells (MSCs) have been highlighted as a new therapy for autoimmune diseases, including rheumatoid arthritis (RA), the disease-specific characteristics of MSCs derived from elderly RA patients are not well understood. METHODS: W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hyeon-Jeong, Lee, Won-Jae, Hwang, Sun-Chul, Choe, Yongho, Kim, Saetbyul, Bok, Eunyeong, Lee, Sangyeob, Kim, Seung-Joon, Kim, Hyun-Ok, Ock, Sun-A, Noh, Hae-Sook, Rho, Gyu-Jin, Lee, Sang-Il, Lee, Sung-Lim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439066/ https://www.ncbi.nlm.nih.gov/pubmed/34521481 http://dx.doi.org/10.1186/s13287-021-02453-z

Ejemplares similares

Metastasis prognostic factors and cancer stem cell-related transcription factors associated with metastasis induction in canine metastatic mammary gland tumors
por: Kim, Saetbyul, et al.
Publicado: (2021)

Insensitive Effects of Inflammatory Cytokines on the Reference Genes of Synovial Fluid Resident-Mesenchymal Stem Cells Derived from Rheumatoid Arthritis Patients
por: Bok, Eun-Yeong, et al.
Publicado: (2023)

Serum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity
por: Lee, Hanna, et al.
Publicado: (2022)

Magnetic resonance imaging-assessed synovial and bone changes in hand and wrist joints of rheumatoid arthritis patients
por: Lee, Kyung-Ann, et al.
Publicado: (2019)

IFN-γ Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application
por: Lee, Hyeon-Jeong, et al.
Publicado: (2021)

Increased Lymphocyte Infiltration in Rheumatoid Arthritis Is Correlated with an Increase in LTi-like Cells in Synovial Fluid
por: Koo, Jihye, et al.
Publicado: (2013)

From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
por: Byun, Hae-Ok, et al.
Publicado: (2015)

Enhanced Immunomodulatory Activity of Gelatin-Encapsulated Rubus coreanus Miquel Nanoparticles
por: Seo, Yong Chang, et al.
Publicado: (2011)

Blockade of translationally controlled tumor protein attenuated the aggressiveness of fibroblast-like synoviocytes and ameliorated collagen-induced arthritis
por: Kim, Mingyo, et al.
Publicado: (2021)

Atomic force microscopy data of novel high-k hydrocarbon films synthesized on Si wafers for gate dielectric applications
por: Kwon, Jihwan, et al.
Publicado: (2020)

Applications of Bioinspired Platforms for Enhancing Immunomodulatory Function of Mesenchymal Stromal Cells
por: Kim, Ok-Hyeon, et al.
Publicado: (2023)

Sirtuin signaling in cellular senescence and aging
por: Lee, Shin-Hae, et al.
Publicado: (2019)

Synovial fluid CD69(+)CD8(+) T cells with tissue‐resident phenotype mediate perforin‐dependent citrullination in rheumatoid arthritis
por: Jung, Jae Hyung, et al.
Publicado: (2020)

Clinical Perspectives of Single-Cell RNA Sequencing
por: Kim, Nayoung, et al.
Publicado: (2021)

BMI1 inhibits senescence and enhances the immunomodulatory properties of human mesenchymal stem cells via the direct suppression of MKP-1/DUSP1
por: Lee, Jin Young, et al.
Publicado: (2016)

Differences in Clinical and Dietary Characteristics, Serum Adipokine Levels, and Metabolomic Profiles between Early- and Late-Onset Gout
por: Suh, Young Sun, et al.
Publicado: (2021)

Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis
por: Kim, Hye Young, et al.
Publicado: (2014)

IL-17-mediated mitochondrial dysfunction impairs apoptosis in rheumatoid arthritis synovial fibroblasts through activation of autophagy
por: Kim, Eun Kyung, et al.
Publicado: (2017)

Senescent tumor cells building three-dimensional tumor clusters
por: Lee, Hyun-Gyu, et al.
Publicado: (2018)

Overexpression of Oct4 in porcine ovarian stem/stromal cells enhances differentiation of oocyte-like cells in vitro and ovarian follicular formation in vivo
por: Lee, Yeon-Mi, et al.
Publicado: (2016)

Nursing leaders' perceptions of the state of nursing leadership and the need for nursing leadership education reform: A qualitative content analysis from South Korea
por: Kim, Hae‐Ok, et al.
Publicado: (2022)

Retraction: Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis
por: Kim, Hye Young, et al.
Publicado: (2020)

Uncalcified Synovial Chondromatosis in the Pisotriquetral Joint
por: Kim, Hyo-Kon, et al.
Publicado: (2015)

The role of senescence of bone marrow cells in acute kidney injury
por: Lee, Junyong, et al.
Publicado: (2019)

Differential regulation of senescence and in vitro differentiation by 17β-estradiol between mesenchymal stem cells derived from male and female mini-pigs
por: Lee, Won-Jae, et al.
Publicado: (2016)

Rheumatoid Synovial Fluid and Acidic Extracellular pH Modulate the Immunomodulatory Activity of Urine-Derived Stem Cells
por: Cehakova, Michaela, et al.
Publicado: (2023)

Induced neural stem cells from human patient-derived fibroblasts attenuate neurodegeneration in Niemann-Pick type C mice
por: Hong, Saetbyul, et al.
Publicado: (2021)

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
por: Del Rey, Manuel J., et al.
Publicado: (2019)

Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue
por: Ock, Sun-A, et al.
Publicado: (2016)

Functional Phenotype of Synovial Monocytes Modulating Inflammatory T-Cell Responses in Rheumatoid Arthritis (RA)
por: Yoon, Bo Ruem, et al.
Publicado: (2014)

Female Germ Cell Development, Functioning and Associated Adversities under Unfavorable Circumstances
por: Bharti, Dinesh, et al.
Publicado: (2021)

Immunomodulatory Effects of Balneotherapy with Hae-Un-Dae Thermal Water on Imiquimod-Induced Psoriasis-Like Murine Model
por: Lee, Young Bok, et al.
Publicado: (2014)

Promoter polymorphism (−590, T/C) of interleukin 4 (IL4) gene is associated with rheumatoid arthritis: An updated meta-analysis
por: Park, Hyun Kyung, et al.
Publicado: (2017)

Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells
por: Seok, Jin, et al.
Publicado: (2020)

Data Configuration and Publication Trends for the Korean National Health Insurance and Health Insurance Review & Assessment Database
por: Kim, Hae Kyung, et al.
Publicado: (2020)

Dental pulp-derived stem cells can counterbalance peripheral nerve injury-induced oxidative stress and supraspinal neuro-inflammation in rat brain
por: Ullah, Imran, et al.
Publicado: (2018)

A Case of Rheumatoid Vasculitis Involving Hepatic Artery in Early Rheumatoid Arthritis
por: Lee, Ji-Eun, et al.
Publicado: (2017)

Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium
por: Shin, Mi-Rae, et al.
Publicado: (2021)

Immunomodulatory Effects of Liriope Platyphylla Water Extract on Lipopolysaccharide-Activated Mouse Macrophage
por: Kim, Hye Kyung, et al.
Publicado: (2012)

Immunomodulatory Effects of Hypocrellin A on MHC-restricted Antigen Processing
por: Park, Sunim, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kcfpsu1e168h2kcb5qf2v24cfq