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Uptake of Aβ by OATPs might be a new pathophysiological mechanism of Alzheimer disease

BACKGROUND: The accumulation of neurotoxic amyloid-beta (Aβ) in the brain is a characteristic of Alzheimer's disease (AD), at the same time, it is possible alterations of liver function could affect brain Aβ levels through changes in blood Aβ concentration. Over the last decade, a number of rep...

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Detalles Bibliográficos
Autores principales: Wen, Jinhua, Zhao, Menghua, Sun, Wenxiong, Cheng, Xiaohua, Yu, Luyi, Cao, Duanwen, Li, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439072/
https://www.ncbi.nlm.nih.gov/pubmed/34521342
http://dx.doi.org/10.1186/s12868-021-00658-9