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Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion

Infection with Japanese encephalitis virus (JEV) induces high morbidity and mortality, including potentially permanent neurological sequelae. However, the mechanisms by which viruses cross the blood-brain barrier (BBB) and invade into the central nervous system (CNS) remain unclear. Here, we show th...

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Detalles Bibliográficos
Autores principales: Zou, Song-Song, Zou, Qing-Cui, Xiong, Wen-Jing, Cui, Ning-Yi, Wang, Ke, Liu, Hao-Xuan, Lou, Wen-Juan, Higazy, Doaa, Zhang, Ya-Ge, Cui, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439198/
https://www.ncbi.nlm.nih.gov/pubmed/34532298
http://dx.doi.org/10.3389/fcimb.2021.701820