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Brain-targeting delivery of MMB4 DMS using carrier-free nanomedicine CRT-MMB4@MDZ

Brain-targeting delivery of 1,1′-methylenebis[4-[(hydroxyimino)methyl]-pyridinium] dimethanesulfonate (MMB4 DMS) is limited by its hydrophilic property and chemical instability. In order to solve this problem, herein, we develop a facile protocol through combining antisolvent precipitation and emuls...

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Detalles Bibliográficos
Autores principales: Du, Yimeng, Gao, Jing, Zhang, Hui, Meng, Xiaohui, Qiu, Dong, Gao, Xiang, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439216/
https://www.ncbi.nlm.nih.gov/pubmed/34515590
http://dx.doi.org/10.1080/10717544.2021.1968977