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Brain-targeting delivery of MMB4 DMS using carrier-free nanomedicine CRT-MMB4@MDZ
Brain-targeting delivery of 1,1′-methylenebis[4-[(hydroxyimino)methyl]-pyridinium] dimethanesulfonate (MMB4 DMS) is limited by its hydrophilic property and chemical instability. In order to solve this problem, herein, we develop a facile protocol through combining antisolvent precipitation and emuls...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439216/ https://www.ncbi.nlm.nih.gov/pubmed/34515590 http://dx.doi.org/10.1080/10717544.2021.1968977 |