Cargando…

Edaravone prevents high glucose-induced injury in retinal Müller cells through thioredoxin1 and the PGC-1α/NRF1/TFAM pathway

CONTEXT: Oxidative injury in a high-glucose (HG) environment may be a mechanism of diabetic retinopathy (DR) and edaravone can protect retinal ganglion cells by scavenging ROS. OBJECTIVE: To explore the effect of edaravone on HG-induced injury. MATERIALS AND METHODS: First, Müller cells were culture...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Juanping, Chen, Xinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439237/
https://www.ncbi.nlm.nih.gov/pubmed/34506218
http://dx.doi.org/10.1080/13880209.2021.1972123