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Site-specific acylation of a bacterial virulence regulator attenuates infection

Microbiota generates millimolar concentrations of short-chain fatty acids (SCFAs) that can modulate host metabolism, immunity and susceptibility to infection. Butyrate in particular can function as a carbon source and anti-inflammatory metabolite, but the mechanism by which it inhibits pathogen viru...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenrun J., Pedicord, Virginia A., Peng, Tao, Hang, Howard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439376/
https://www.ncbi.nlm.nih.gov/pubmed/31740807
http://dx.doi.org/10.1038/s41589-019-0392-5