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Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway

Since obesity impairs wound closure and adipose-derived exosomes (ADEs) regulate wound healing in clinical applications, we hypothesized that ADEs may inhibit adipogenesis of adipose-derived stem cells (ADSCs) to reduce the adverse effects of obesity on wound healing. Hedgehog (Hh) signaling has bee...

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Detalles Bibliográficos
Autores principales: Ji, Ziwan, Cai, Zhongming, Gu, Shuming, He, Yucang, Zhang, Zikai, Li, Tian, Wei, Qing, Wang, Jingping, Ke, Chen, Li, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439418/
https://www.ncbi.nlm.nih.gov/pubmed/34532316
http://dx.doi.org/10.3389/fbioe.2021.734810