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Analysis of amyloid-like secondary structure in the Cryab-R120G knock-in mouse model of hereditary cataracts by two-dimensional infrared spectroscopy

αB-crystallin is a small heat shock protein that forms a heterooligomeric complex with αA-crystallin in the ocular lens. It is also widely distributed in tissues throughout the body and has been linked with neurodegenerative diseases such as Alzheimer’s, where it is associated with amyloid fibrils....

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Detalles Bibliográficos
Autores principales: Alperstein, Ariel M., Molnar, Kathleen S., Dicke, Sidney S., Farrell, Kieran M., Makley, Leah N., Zanni, Martin T., Andley, Usha P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439473/
https://www.ncbi.nlm.nih.gov/pubmed/34520490
http://dx.doi.org/10.1371/journal.pone.0257098