Functional human genes typically exhibit epigenetic conservation

Recent DepMap CRISPR-Cas9 single gene disruptions have identified genes more essential to proliferation in tissue culture. It would be valuable to translate these finding with measurements more practical for human tissues. Here we show that DepMap essential genes and other literature curated functio...

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Detalles Bibliográficos
Autores principales: Rud, Daniel, Marjoram, Paul, Siegmund, Kimberly, Shibata, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439480/
https://www.ncbi.nlm.nih.gov/pubmed/34520456
http://dx.doi.org/10.1371/journal.pone.0253250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439480/
https://www.ncbi.nlm.nih.gov/pubmed/34520456
http://dx.doi.org/10.1371/journal.pone.0253250

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