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Regulation of human mTOR complexes by DEPTOR

The vertebrate-specific DEP domain-containing mTOR interacting protein (DEPTOR), an oncoprotein or tumor suppressor, has important roles in metabolism, immunity, and cancer. It is the only protein that binds and regulates both complexes of mammalian target of rapamycin (mTOR), a central regulator of...

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Detalles Bibliográficos
Autores principales: Wälchli, Matthias, Berneiser, Karolin, Mangia, Francesca, Imseng, Stefan, Craigie, Louise-Marie, Stuttfeld, Edward, Hall, Michael N, Maier, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439649/
https://www.ncbi.nlm.nih.gov/pubmed/34519268
http://dx.doi.org/10.7554/eLife.70871