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Regulation of human mTOR complexes by DEPTOR
The vertebrate-specific DEP domain-containing mTOR interacting protein (DEPTOR), an oncoprotein or tumor suppressor, has important roles in metabolism, immunity, and cancer. It is the only protein that binds and regulates both complexes of mammalian target of rapamycin (mTOR), a central regulator of...
Autores principales: | Wälchli, Matthias, Berneiser, Karolin, Mangia, Francesca, Imseng, Stefan, Craigie, Louise-Marie, Stuttfeld, Edward, Hall, Michael N, Maier, Timm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439649/ https://www.ncbi.nlm.nih.gov/pubmed/34519268 http://dx.doi.org/10.7554/eLife.70871 |
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