Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

Microsatellite expansions of CCTG repeats in the cellular nucleic acid-binding protein (CNBP) gene leads to accumulation of toxic RNA and have been associated with myotonic dystrophy type 2 (DM2). However, it is still unclear whether the dystrophic phenotype is also linked to CNBP decrease, a conser...

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Detalles Bibliográficos
Autores principales: Coni, Sonia, Falconio, Federica A, Marzullo, Marta, Munafò, Marzia, Zuliani, Benedetta, Mosti, Federica, Fatica, Alessandro, Ianniello, Zaira, Bordone, Rosa, Macone, Alberto, Agostinelli, Enzo, Perna, Alessia, Matkovic, Tanja, Sigrist, Stephan, Silvestri, Gabriella, Canettieri, Gianluca, Ciapponi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439652/
https://www.ncbi.nlm.nih.gov/pubmed/34517941
http://dx.doi.org/10.7554/eLife.69269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439652/
https://www.ncbi.nlm.nih.gov/pubmed/34517941
http://dx.doi.org/10.7554/eLife.69269

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