An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

Fucose is a common component of eukaryotic cell-surface glycoconjugates, generally added by Golgi-resident fucosyltransferases. Whereas fucosylated glycoconjugates are rare in kinetoplastids, the biosynthesis of the nucleotide sugar GDP-Fuc has been shown to be essential in Trypanosoma brucei. Here...

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Detalles Bibliográficos
Autores principales: Bandini, Giulia, Damerow, Sebastian, Sempaio Guther, Maria Lucia, Guo, Hongjie, Mehlert, Angela, Paredes Franco, Jose Carlos, Beverley, Stephen, Ferguson, Michael AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439653/
https://www.ncbi.nlm.nih.gov/pubmed/34410224
http://dx.doi.org/10.7554/eLife.70272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439653/
https://www.ncbi.nlm.nih.gov/pubmed/34410224
http://dx.doi.org/10.7554/eLife.70272

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