Early-Onset Cerebral Amyloid Angiopathy and Alzheimer Disease Related to an APP Locus Triplication

BACKGROUND AND OBJECTIVE: To report a triplication of the amyloid-β precursor protein (APP) locus along with relative messenger RNA (mRNA) expression in a family with autosomal dominant early-onset cerebral amyloid angiopathy (CAA) and Alzheimer disease (AD). METHODS: Four copies of the APP gene wer...

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Detalles Bibliográficos
Autores principales: Grangeon, Lou, Cassinari, Kévin, Rousseau, Stéphane, Croisile, Bernard, Formaglio, Maïté, Moreaud, Olivier, Boutonnat, Jean, Le Meur, Nathalie, Miné, Manuele, Coste, Thibault, Pipiras, Eva, Tournier-Lasserve, Elisabeth, Rovelet-Lecrux, Anne, Campion, Dominique, Wallon, David, Nicolas, Gael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439959/
https://www.ncbi.nlm.nih.gov/pubmed/34532568
http://dx.doi.org/10.1212/NXG.0000000000000609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439959/
https://www.ncbi.nlm.nih.gov/pubmed/34532568
http://dx.doi.org/10.1212/NXG.0000000000000609

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