FOXA1 Suppresses SATB1 Transcription and Inactivates the Wnt/β-Catenin Pathway to Alleviate Diabetic Nephropathy in a Mouse Model

OBJECTIVE: Diabetic nephropathy (DN) represents the most common diabetic complication that may lead to end-stage renal disease. This work focused on the effect of FOXA1 on the DN development and the molecular mechanism. METHODS: A mouse model of DN was induced by high-fat diets and streptozotocin. T...

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Detalles Bibliográficos
Autores principales: Zhu, Hong, Peng, Jiarui, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439979/
https://www.ncbi.nlm.nih.gov/pubmed/34531670
http://dx.doi.org/10.2147/DMSO.S314709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439979/
https://www.ncbi.nlm.nih.gov/pubmed/34531670
http://dx.doi.org/10.2147/DMSO.S314709

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