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FOXA1 Suppresses SATB1 Transcription and Inactivates the Wnt/β-Catenin Pathway to Alleviate Diabetic Nephropathy in a Mouse Model
OBJECTIVE: Diabetic nephropathy (DN) represents the most common diabetic complication that may lead to end-stage renal disease. This work focused on the effect of FOXA1 on the DN development and the molecular mechanism. METHODS: A mouse model of DN was induced by high-fat diets and streptozotocin. T...
Autores principales: | Zhu, Hong, Peng, Jiarui, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439979/ https://www.ncbi.nlm.nih.gov/pubmed/34531670 http://dx.doi.org/10.2147/DMSO.S314709 |
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