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Nuclear Dbf2-related Kinase 1 functions as tumor suppressor in glioblastoma by phosphorylation of Yes-associated protein

BACKGROUND: The Nuclear Dbf2-related (NDR1) kinase is a member of the NDR/LATS family, which was a supplementary of Hippo pathway. However, whether NDR1 could inhibit glioblastoma (GBM) growth by phosphorylating Yes-associated protein (YAP) remains unknown. Meanwhile, the role of NDR1 in GBM was not...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Liu, Bin, Yu, Tao, Han, Yun-Feng, Wu, Chao, Wang, Zhen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440018/
https://www.ncbi.nlm.nih.gov/pubmed/34343153
http://dx.doi.org/10.1097/CM9.0000000000001653