GABA-A receptor differences in schizophrenia: a positron emission tomography study using [(11)C]Ro154513

A loss of GABA signaling is a prevailing hypothesis for the pathogenesis of schizophrenia. Preclinical studies indicate that blockade of the α5 subtype of the GABA receptor (α5-GABA(A)Rs) leads to behavioral phenotypes associated with schizophrenia, and postmortem evidence indicates lower hippocampa...

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Detalles Bibliográficos
Autores principales: Marques, Tiago Reis, Ashok, Abhishekh H., Angelescu, Ilinca, Borgan, Faith, Myers, Jim, Lingford-Hughes, Anne, Nutt, David J., Veronese, Mattia, Turkheimer, Federico E., Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440185/
https://www.ncbi.nlm.nih.gov/pubmed/32296127
http://dx.doi.org/10.1038/s41380-020-0711-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440185/
https://www.ncbi.nlm.nih.gov/pubmed/32296127
http://dx.doi.org/10.1038/s41380-020-0711-y

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