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A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells

INTRODUCTION: Osteosarcoma is the most common primary malignancy of the bone among adolescents and children. Despite intensive chemotherapy and aggressive surgery, the 5-year survival rate of osteosarcoma still falls under 70%, mainly due to its tendency to metastasize and to develop drug resistance...

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Detalles Bibliográficos
Autores principales: Chen, Weijie, Wu, Su, Huang, Yang, Zhang, Tingting, Dong, Hao, Zheng, Xing, Chen, Tao, Gong, Xiaokang, Liu, Gang, Zhao, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440230/
https://www.ncbi.nlm.nih.gov/pubmed/34531665
http://dx.doi.org/10.2147/OTT.S317122