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Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity

SARS-CoV-2 infection in children is less severe than it is in adults. We perform a longitudinal analysis of the early innate responses in children and adults with mild infection within household clusters. Children display fewer symptoms than adults do, despite similar initial viral load, and mount a...

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Detalles Bibliográficos
Autores principales: Vono, Maria, Huttner, Angela, Lemeille, Sylvain, Martinez-Murillo, Paola, Meyer, Benjamin, Baggio, Stephanie, Sharma, Shilpee, Thiriard, Anais, Marchant, Arnaud, Godeke, Gert-Jan, Reusken, Chantal, Alvarez, Catia, Perez-Rodriguez, Francisco, Eckerle, Isabella, Kaiser, Laurent, Loevy, Natasha, Eberhardt, Christiane S., Blanchard-Rohner, Geraldine, Siegrist, Claire-Anne, Didierlaurent, Arnaud M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440231/
https://www.ncbi.nlm.nih.gov/pubmed/34587479
http://dx.doi.org/10.1016/j.celrep.2021.109773