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Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity
SARS-CoV-2 infection in children is less severe than it is in adults. We perform a longitudinal analysis of the early innate responses in children and adults with mild infection within household clusters. Children display fewer symptoms than adults do, despite similar initial viral load, and mount a...
Autores principales: | Vono, Maria, Huttner, Angela, Lemeille, Sylvain, Martinez-Murillo, Paola, Meyer, Benjamin, Baggio, Stephanie, Sharma, Shilpee, Thiriard, Anais, Marchant, Arnaud, Godeke, Gert-Jan, Reusken, Chantal, Alvarez, Catia, Perez-Rodriguez, Francisco, Eckerle, Isabella, Kaiser, Laurent, Loevy, Natasha, Eberhardt, Christiane S., Blanchard-Rohner, Geraldine, Siegrist, Claire-Anne, Didierlaurent, Arnaud M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440231/ https://www.ncbi.nlm.nih.gov/pubmed/34587479 http://dx.doi.org/10.1016/j.celrep.2021.109773 |
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