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Dose escalation study of targeted alpha therapy with [(225)Ac]Ac-DOTA-substance P in recurrence glioblastoma – safety and efficacy

ABSTRACT: Glioblastoma is the most common and malignant primary brain tumour, with a poor prognosis. Introduction of new treatment options is critically important. The study aimed to assess the appropriateness of escalation doses and toxicity of [(225)Ac]Ac-DOTA-SP therapy. MATERIAL AND METHODS: A t...

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Detalles Bibliográficos
Autores principales: Królicki, Leszek, Bruchertseifer, Frank, Kunikowska, Jolanta, Koziara, Henryk, Pawlak, Dariusz, Kuliński, Radosław, Rola, Rafał, Merlo, Adrian, Morgenstern, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440247/
https://www.ncbi.nlm.nih.gov/pubmed/33860346
http://dx.doi.org/10.1007/s00259-021-05350-y