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Specific and non-specific binding of a tracer for the translocator-specific protein in schizophrenia: an [11C]-PBR28 blocking study

OBJECTIVE: The mitochondrial 18-kDa translocator protein (TSPO) is expressed by activated microglia and positron emission tomography enables the measurement of TSPO levels in the brain. Findings in schizophrenia have shown to vary depending on the outcome measure used and this discrepancy in TSPO re...

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Detalles Bibliográficos
Autores principales: Marques, Tiago Reis, Veronese, Mattia, Owen, David R., Rabiner, Eugenii A., Searle, Graham E., Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440284/
https://www.ncbi.nlm.nih.gov/pubmed/33825022
http://dx.doi.org/10.1007/s00259-021-05327-x