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Therapeutic targeting of the inflammasome in myeloid malignancies

Even though genetic perturbations and mutations are important for the development of myeloid malignancies, the effects of an inflammatory microenvironment are a critical modulator of carcinogenesis. Activation of the innate immune system through various ligands and signaling pathways is an important...

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Detalles Bibliográficos
Autores principales: Chakraborty, Samarpana, Shapiro, Lauren C., de Oliveira, Sofia, Rivera-Pena, Bianca, Verma, Amit, Shastri, Aditi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440507/
https://www.ncbi.nlm.nih.gov/pubmed/34521810
http://dx.doi.org/10.1038/s41408-021-00547-8