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Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data

Estimation of direct and indirect (i.e. parental and/or sibling) genetic effects on phenotypes is becoming increasingly important. We compare several multivariate methods that utilize summary results statistics from genome-wide association studies to determine how well they estimate direct and indir...

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Detalles Bibliográficos
Autores principales: Warrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G., Evans, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440517/
https://www.ncbi.nlm.nih.gov/pubmed/34521848
http://dx.doi.org/10.1038/s41467-021-25723-z