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Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data
Estimation of direct and indirect (i.e. parental and/or sibling) genetic effects on phenotypes is becoming increasingly important. We compare several multivariate methods that utilize summary results statistics from genome-wide association studies to determine how well they estimate direct and indir...
Autores principales: | Warrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G., Evans, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440517/ https://www.ncbi.nlm.nih.gov/pubmed/34521848 http://dx.doi.org/10.1038/s41467-021-25723-z |
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