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Development of a highly sensitive chemiluminescent enzyme immunoassay for fragmented cytokeratin 18 using new antibodies

Fragmented cytokeratin 18 (fCK18) released from epithelial cells undergoing apoptosis is widely studied in various diseases. However, fCK18 measurement is not utilized in clinical practice due to imprecise disease-state cutoff values. Therefore, we set out to generate new monoclonal antibodies (mAbs...

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Detalles Bibliográficos
Autores principales: Yamada, Minori, Eguchi, Akiko, Okuno, Koji, Sakaguchi, Koji, Yamaguchi, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440549/
https://www.ncbi.nlm.nih.gov/pubmed/34521905
http://dx.doi.org/10.1038/s41598-021-97439-5