Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma

Multiple myeloma is a genetically heterogeneous cancer of the bone marrow plasma cells (PC). Distinct myeloma transcriptome profiles are primarily driven by myeloma initiating events (MIE) and converge into a mutually exclusive overexpression of the CCND1 and CCND2 oncogenes. Here, with reference to...

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Detalles Bibliográficos
Autores principales: Alvarez-Benayas, Jaime, Trasanidis, Nikolaos, Katsarou, Alexia, Ponnusamy, Kanagaraju, Chaidos, Aristeidis, May, Philippa C., Xiao, Xiaolin, Bua, Marco, Atta, Maria, Roberts, Irene A. G., Auner, Holger W., Hatjiharissi, Evdoxia, Papaioannou, Maria, Caputo, Valentina S., Sudbery, Ian M., Karadimitris, Anastasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440555/
https://www.ncbi.nlm.nih.gov/pubmed/34521827
http://dx.doi.org/10.1038/s41467-021-25704-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440555/
https://www.ncbi.nlm.nih.gov/pubmed/34521827
http://dx.doi.org/10.1038/s41467-021-25704-2

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