The role of DNA-binding and ARNT dimerization on the nucleo-cytoplasmic translocation of the aryl hydrocarbon receptor

The human aryl hydrocarbon receptor (AHR) is predominantly located in the cytoplasm, while activation depends on its nuclear translocation. Binding to endogenous or xenobiotic ligands terminates the basal nucleo-cytoplasmic shuttling and stabilizes an exclusive nuclear population. The precise mechan...

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Detalles Bibliográficos
Autores principales: Haidar, Rashad, Henkler, Frank, Kugler, Josephine, Rosin, Aline, Genkinger, Doris, Laux, Peter, Luch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440571/
https://www.ncbi.nlm.nih.gov/pubmed/34521881
http://dx.doi.org/10.1038/s41598-021-97507-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440571/
https://www.ncbi.nlm.nih.gov/pubmed/34521881
http://dx.doi.org/10.1038/s41598-021-97507-w

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