Evaluation of acute and subacute toxicity of ethanolic extract and fraction of alkaloids from bark of Aspidosperma nitidum in mice

This study investigated the acute and subacute toxicity of the ethanolic extract (EE) and alkaloid fraction (FA) from A. nitidum. The EE was obtained from trunk bark with ethanol, FA was obtained from the fractionation of EE. To test the acute toxicity, mice were divided into four groups, and the ne...

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Detalles Bibliográficos
Autores principales: Brígido, Heliton Patrick Cordovil, Varela, Everton Luiz Pompeu, Gomes, Antônio Rafael Quadros, Bastos, Mirian Letícia Carmo, de Oliveira Feitosa, Andre, do Rosário Marinho, Andrey Moacir, Carneiro, Liliane Almeida, Coelho-Ferreira, Márlia Regina, Dolabela, Maria Fâni, Percário, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440572/
https://www.ncbi.nlm.nih.gov/pubmed/34521944
http://dx.doi.org/10.1038/s41598-021-97637-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440572/
https://www.ncbi.nlm.nih.gov/pubmed/34521944
http://dx.doi.org/10.1038/s41598-021-97637-1

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