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Evaluation of acute and subacute toxicity of ethanolic extract and fraction of alkaloids from bark of Aspidosperma nitidum in mice
This study investigated the acute and subacute toxicity of the ethanolic extract (EE) and alkaloid fraction (FA) from A. nitidum. The EE was obtained from trunk bark with ethanol, FA was obtained from the fractionation of EE. To test the acute toxicity, mice were divided into four groups, and the ne...
Autores principales: | Brígido, Heliton Patrick Cordovil, Varela, Everton Luiz Pompeu, Gomes, Antônio Rafael Quadros, Bastos, Mirian Letícia Carmo, de Oliveira Feitosa, Andre, do Rosário Marinho, Andrey Moacir, Carneiro, Liliane Almeida, Coelho-Ferreira, Márlia Regina, Dolabela, Maria Fâni, Percário, Sandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440572/ https://www.ncbi.nlm.nih.gov/pubmed/34521944 http://dx.doi.org/10.1038/s41598-021-97637-1 |
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