AIM2 deficiency in B cells ameliorates systemic lupus erythematosus by regulating Blimp-1–Bcl-6 axis-mediated B-cell differentiation

Absent in melanoma 2 (AIM2) has been reported to be a component of inflammasomes in innate immune cells. Surprisingly, AIM2 is expressed by B cells, and higher AIM2 expression is observed in the B cells from lupus patients. To date, the inflammasome-independent function of AIM2 in B cells remains un...

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Detalles Bibliográficos
Autores principales: Yang, Ming, Long, Di, Hu, Longyuan, Zhao, Zhidan, Li, Qianwen, Guo, Yunkai, He, Zhenghao, Zhao, Ming, Lu, Liwei, Li, Fen, Long, Hai, Wu, Haijing, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440614/
https://www.ncbi.nlm.nih.gov/pubmed/34521812
http://dx.doi.org/10.1038/s41392-021-00725-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440614/
https://www.ncbi.nlm.nih.gov/pubmed/34521812
http://dx.doi.org/10.1038/s41392-021-00725-x

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