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Hypoxia increases KIAA1199/CEMIP expression and enhances cell migration in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is characterised by dense desmoplasia and hypoxic microenvironment. Our previous reports demonstrated that hyaluronan (HA), especially low-molecular-weight HA, provides a favourable microenvironment for PDAC progression. However, the effect of hypoxia on HA me...

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Detalles Bibliográficos
Autores principales: Oba, Takuya, Sato, Norihiro, Adachi, Yasuhiro, Amaike, Takao, Kudo, Yuzan, Koga, Atsuhiro, Kohi, Shiro, Hirata, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440617/
https://www.ncbi.nlm.nih.gov/pubmed/34521918
http://dx.doi.org/10.1038/s41598-021-97752-z