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Parental relatedness through time revealed by runs of homozygosity in ancient DNA

Parental relatedness of present-day humans varies substantially across the globe, but little is known about the past. Here we analyze ancient DNA, leveraging that parental relatedness leaves genomic traces in the form of runs of homozygosity. We present an approach to identify such runs in low-cover...

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Detalles Bibliográficos
Autores principales: Ringbauer, Harald, Novembre, John, Steinrücken, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440622/
https://www.ncbi.nlm.nih.gov/pubmed/34521843
http://dx.doi.org/10.1038/s41467-021-25289-w