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The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash

Previous studies have suggested that the pneumococcal niche changes from the nasopharynx to the oral cavity with age. We use an Experimental Human Pneumococcal Challenge model to investigate pneumococcal colonisation in different anatomical niches with age. Healthy adults (n = 112) were intranasally...

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Detalles Bibliográficos
Autores principales: Nikolaou, Elissavet, German, Esther L., Blizard, Annie, Howard, Ashleigh, Hitchins, Lisa, Chen, Tao, Chadwick, Jim, Pojar, Sherin, Mitsi, Elena, Solórzano, Carla, Sunny, Syba, Dunne, Felicity, Gritzfeld, Jenna F., Adler, Hugh, Hinds, Jason, Gould, Katherine A., Rylance, Jamie, Collins, Andrea M., Gordon, Stephen B., Ferreira, Daniela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440778/
https://www.ncbi.nlm.nih.gov/pubmed/34521967
http://dx.doi.org/10.1038/s41598-021-97807-1