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The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash
Previous studies have suggested that the pneumococcal niche changes from the nasopharynx to the oral cavity with age. We use an Experimental Human Pneumococcal Challenge model to investigate pneumococcal colonisation in different anatomical niches with age. Healthy adults (n = 112) were intranasally...
Autores principales: | Nikolaou, Elissavet, German, Esther L., Blizard, Annie, Howard, Ashleigh, Hitchins, Lisa, Chen, Tao, Chadwick, Jim, Pojar, Sherin, Mitsi, Elena, Solórzano, Carla, Sunny, Syba, Dunne, Felicity, Gritzfeld, Jenna F., Adler, Hugh, Hinds, Jason, Gould, Katherine A., Rylance, Jamie, Collins, Andrea M., Gordon, Stephen B., Ferreira, Daniela M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440778/ https://www.ncbi.nlm.nih.gov/pubmed/34521967 http://dx.doi.org/10.1038/s41598-021-97807-1 |
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