Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway

Liver fibrosis is an important stage in the progression of liver injury into cirrhosis or even liver cancer. Hepatic stellate cells (HSCs) are induced by transforming growth factor-β1 (TGF-β1) to produce α-smooth muscle actin (α-SMA) and collagens in liver fibrosis. Butaselen (BS), which was previou...

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Detalles Bibliográficos
Autores principales: Jiao, Wenxuan, Bai, Man, Yin, Hanwei, Liu, Jiayi, Sun, Jing, Su, Xiaoxia, Zeng, Huihui, Wen, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440796/
https://www.ncbi.nlm.nih.gov/pubmed/34540892
http://dx.doi.org/10.3389/fmolb.2021.690170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440796/
https://www.ncbi.nlm.nih.gov/pubmed/34540892
http://dx.doi.org/10.3389/fmolb.2021.690170

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