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Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa

Intranasal delivery has gained prominence since 1990, when the olfactory mucosa was recognized as the window to the brain and the central nervous system (CNS); this has enabled the direct site specific targeting of neurological diseases for the first time. Intranasal delivery is a promising route be...

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Detalles Bibliográficos
Autores principales: Spindler, Lena Marie, Feuerhake, Andreas, Ladel, Simone, Günday, Cemre, Flamm, Johannes, Günday-Türeli, Nazende, Türeli, Emre, Tovar, Günter E. M., Schindowski, Katharina, Gruber-Traub, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440808/
https://www.ncbi.nlm.nih.gov/pubmed/34539414
http://dx.doi.org/10.3389/fphar.2021.732954