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Development of Tinnitus and Hyperacusis in a Mouse Model of Tobramycin Cochleotoxicity

Aminoglycosides (AG) antibiotics are a common treatment for recurrent infections in cystic fibrosis (CF) patients. AGs are highly ototoxic, resulting in a range of auditory dysfunctions. It was recently shown that the acoustic startle reflex (ASR) can assess behavioral evidence of hyperacusis and ti...

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Detalles Bibliográficos
Autores principales: Longenecker, Ryan J., Gu, Rende, Homan, Jennifer, Kil, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440845/
https://www.ncbi.nlm.nih.gov/pubmed/34539342
http://dx.doi.org/10.3389/fnmol.2021.715952