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The ryanodine receptor stabilizer S107 ameliorates contractility of adult Rbm20 knockout rat cardiomyocytes

RNA binding motif 20 (RBM20) cardiomyopathy has been detected in approximately 3% of populations afflicted with dilated cardiomyopathy (DCM). It is well conceived that RBM20 cardiomyopathy is provoked by titin isoform switching in combination with resting Ca(2+) leaking. In this study, we characteri...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhu, Chaoqun, Yin, Zhiyong, Zhang, Yanghai, Wang, Chunyan, Walk, Andrea Sanchez, Lin, Ying‐Hsi, McKinsey, Timothy A., Woulfe, Kathleen C., Ren, Jun, Chew, Herbert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440945/
https://www.ncbi.nlm.nih.gov/pubmed/34523260
http://dx.doi.org/10.14814/phy2.15011