Sustained Baclofen-Induced Activation of GABA(B) Receptors After Cerebral Ischemia Restores Receptor Expression and Function and Limits Progressing Loss of Neurons

One important function of GABA(B) receptors is the control of neuronal activity to prevent overexcitation and thereby excitotoxic death, which is a hallmark of cerebral ischemia. Consequently, sustained activation of GABA(B) receptors with the selective agonist baclofen provides neuroprotection in i...

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Detalles Bibliográficos
Autores principales: Hleihil, Mohammad, Vaas, Markus, Bhat, Musadiq A., Balakrishnan, Karthik, Benke, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440977/
https://www.ncbi.nlm.nih.gov/pubmed/34539344
http://dx.doi.org/10.3389/fnmol.2021.726133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440977/
https://www.ncbi.nlm.nih.gov/pubmed/34539344
http://dx.doi.org/10.3389/fnmol.2021.726133

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