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Effective Antidepressant Chronotherapeutics (Sleep Deprivation and Light Therapy) Normalize the IL-1β:IL-1ra Ratio in Bipolar Depression

BACKGROUND: Mood disorders associate with peripheral markers of low-grade inflammation, among which circulating levels of interleukin-1β (IL-1β) consistently predict diagnosis and poor outcomes. Antidepressant chronotherapeutics (total sleep deprivation and light therapy, TSD+LT) prompts response in...

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Detalles Bibliográficos
Autores principales: Benedetti, Francesco, Dallaspezia, Sara, Melloni, Elisa Maria Teresa, Lorenzi, Cristina, Zanardi, Raffaella, Barbini, Barbara, Colombo, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440979/
https://www.ncbi.nlm.nih.gov/pubmed/34539454
http://dx.doi.org/10.3389/fphys.2021.740686