Nuclear Aurora kinase A triggers programmed death‐ligand 1‐mediated immune suppression by activating MYC transcription in triple‐negative breast cancer

BACKGROUND: Increasing studies have reported that oncogenes regulate components of the immune system, suggesting that this is a mechanism for tumorigenesis. Aurora kinase A (AURKA), a serine/threonine kinase, is involved in cell mitosis and is essential for tumor cell proliferation, metastasis, and...

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Detalles Bibliográficos
Autores principales: Sun, Shulan, Zhou, Wei, Li, Xiaoxi, Peng, Fei, Yan, Min, Zhan, Yajing, An, Fan, Li, Xiaoyan, Liu, Yunyong, Liu, Quentin, Piao, Haozhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441052/
https://www.ncbi.nlm.nih.gov/pubmed/34251762
http://dx.doi.org/10.1002/cac2.12190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441052/
https://www.ncbi.nlm.nih.gov/pubmed/34251762
http://dx.doi.org/10.1002/cac2.12190

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