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Intra‐heterogeneity in transcription and chemoresistant property of leukemia‐initiating cells in murine Setd2(−/−) acute myeloid leukemia

BACKGROUND: Heterogeneity of leukemia‐initiating cells (LICs) is a major obstacle in acute myeloid leukemia (AML) therapy. Accumulated evidence indicates that the coexistence of multiple types of LICs with different pathogenicity in the same individual is a common feature in AML. However, the functi...

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Detalles Bibliográficos
Autores principales: Song, Jiachun, Du, Longting, Liu, Ping, Wang, Fuhui, Zhang, Bo, Xie, Yinyin, Lu, Jing, Jin, Yi, Zhou, Yan, Lv, Gang, Zhang, Jianmin, Chen, Saijuan, Chen, Zhu, Sun, Xiaojian, Zhang, Yuanliang, Huang, Qiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441059/
https://www.ncbi.nlm.nih.gov/pubmed/34196511
http://dx.doi.org/10.1002/cac2.12189