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An intermediate state in trans-differentiation with proliferation, metabolic, and epigenetic switching

Although TGF-β signaling can effectively activate fibroblasts to transform to myofibroblasts, the underlying mechanisms involved in the cell fate switching for trans-differentiation have not been fully elucidated. In this study, we found the evidence of an intermediate state in the process of trans-...

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Detalles Bibliográficos
Autores principales: Ye, Zhikai, Li, Wenbo, Jiang, Zhenlong, Wang, Erkang, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441076/
https://www.ncbi.nlm.nih.gov/pubmed/34541470
http://dx.doi.org/10.1016/j.isci.2021.103057