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An intermediate state in trans-differentiation with proliferation, metabolic, and epigenetic switching
Although TGF-β signaling can effectively activate fibroblasts to transform to myofibroblasts, the underlying mechanisms involved in the cell fate switching for trans-differentiation have not been fully elucidated. In this study, we found the evidence of an intermediate state in the process of trans-...
Autores principales: | Ye, Zhikai, Li, Wenbo, Jiang, Zhenlong, Wang, Erkang, Wang, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441076/ https://www.ncbi.nlm.nih.gov/pubmed/34541470 http://dx.doi.org/10.1016/j.isci.2021.103057 |
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